Treat Various Lesions With a Portable Cryosurgery System
Why send your patients to a specialist when you can treat common warts and skin lesions right in the office?
The Cryo Professional portable cryosurgery system for treatment of different types of benign skin lesions is convenient and cost-effective for physicians and healthcare professionals. Each kit includes cryogenic aerosol canisters, instructions for use, and single-use applicators, providing approximately 50 treatments.
Cryo Professional
Convenient For Patients. Cost‑Effective For You.
Each cryosurgery kit contains cryogenic aerosol canisters with dimethyl ether propane spray, single-use applicators, and instructions for use. The kit typically pays for itself within three to four applications. Cryo Professional is ready to use when you need it.
Cryo Professional Benefits
- Easy to use and takes just minutes
- Results similar to liquid nitrogen
- Low cost per treatment
- Profitable reimbursement
- Ready to use
Cryo Professional Indications and Usage
The Cryo Professional cryosurgery system is cleared to treat a variety of warts and skin lesions, including:
- Verruca vulgaris (common wart)
- Lentigo (age spots)
- Verruca plana (flat wart)
- Keratoses (sun spots)
- Verruca plantaris (plantar wart)
- Acrochordon (skin tags)
- Condyloma (genital warts)
- Molluscum contagiosum (water warts)
Part Numbers and Descriptions
- UTM0400 Mixed Kit
(2) 80mL canisters, (30) 2mm & (30) 5mm applicators - UTM0300 2mm Kit
(2) 80mL canisters, (60) 2mm applicators - UTM0200 5mm Kit
(2) 80mL canisters, (50) 5mm applicators
Download Cryo Professional Resources
Important Risk and Safety Information
Cryo Professional is flammable. Keep away from open flame and other potential ignition sources, including diathermy or other medical equipment. Use in a well-ventilated area. Consult a pediatrician for use on patients 4 and younger. Do not use if uncertain of diagnosis or if there is a possibility of cancer, or on patients with cryoglobulinemia, circulatory issues, or patients using immunosuppressant medication. Do not spray cryogen directly on skin or when applicator tip is in contact with skin. Avoid eye contact. Use only as a system with the supplied applicators. Freezing may alter skin pigmentation. Avoid freezing on peripheral arteries. Carefully read instructions prior to using this product.
CAUTION: Federal law restricts this device to sale by and on the order of a licensed healthcare practitioner.
More About Cryo Professional
Cryo Professional is designed to provide a convenient, effective approach to cryosurgical treatment in a variety of clinical settings. With its portable design and controlled application, it supports healthcare professionals in delivering precise, efficient care for a range of common skin lesions.
In the sections below, explore additional details about Cryo Professional, including how it works, its clinical applications, and key considerations for use.
Key Specs at a Glance
- Onset Time: Seconds
- Treatment Time: 15–40 seconds depending on lesion type
- Contents: DMEP blend in an 80 mL aerosol can
- Treatment Capacity: Approx. 50 applications per kit
- Application Method: Spray-to-applicator
- Indications: Warts, keratoses, molluscum contagiosum, lentigo, and more
Designed for Patient Comfort and Practitioner Ease
Cryo Professional is quiet, fast, and its targeted spray method avoids direct cryogen-to-skin contact, which helps minimize discomfort.
With short treatment times and no tanks or tools, it’s a gentle, efficient option.
Cryo Professional vs. Liquid Nitrogen
Cryo Professional delivers cryosurgical performance comparable to liquid nitrogen, but without the drawbacks of bulk storage, or cryogen tanks.
Designed for simplicity and safety, it uses a non-toxic, non-pressurized dimethyl ether-propane (DMEP) blend and single-use applicators that make it easy for clinicians to apply consistent treatments without refrigeration, electricity, or protective gloves required.
It’s ready to use within seconds and stores easily in tight clinical spaces.
Clinical Track Record
Cryo Professional builds on over a century of innovation from Gebauer, the makers of Gebauer’s Ethyl Chloride®. Backed by evidence and practice, Cryo Professional has demonstrated safety and efficacy in both pediatric and adult dermatologic care. It’s trusted for treating a wide range of skin lesions and can deliver a profitable return after just a few uses.
When to Choose Cryo Professional
Choose Cryo Professional when you need a safe, effective, and portable solution for treating benign skin lesions. It’s ideal for pediatric practices, urgent care, dermatology, and mobile health units and useful when time, space, and patient comfort are top priorities.
It’s also a smart alternative when liquid nitrogen systems are too costly, cumbersome, or impractical.
Cryo Professional Contents and Cost Per Treatment
Each Cryo Professional kit includes two 80 mL canisters and single-use applicators (quantities vary by kit type). Treatment costs are minimal. Kits typically pay for themselves in 3–4 uses, with up to 50+ treatments per kit.
Reimbursement rates vary by CPT code but can exceed $5,000 per kit depending on lesion type.
Evolution of Cryo Professional
Originally developed under the name Histofreezer®, the Cryo Professional system reflects Gebauer’s legacy of refining patient comfort tools. What started as a simpler alternative to liquid nitrogen has evolved into a precision-engineered solution with clinical-grade spray control, ergonomic handling, and a growing role in pediatric and outpatient dermatology care.
Storage, Shelf Life, Shipping
- Storage: Store tightly sealed in a cool, ventilated space away from temperatures above 122°F (50°C)
- Shelf Life: Up to 3 years from manufacturing date
- Shipping: Classified as UN1950 AEROSOLS — flammable; special care required for transport
- Disposal: Follow hazardous waste protocols. Do not puncture or incinerate
Safety Facts
- Refrigerant: Non-toxic dimethyl ether-propane blend
- Flammable: Yes – keep away from heat or electrical cautery equipment
- Use only on: Patients age 4+ with benign lesions on intact skin
- Do NOT use: On suspicious or pigmented lesions, or patients with circulatory issues, cryoglobulinemia, or immunosuppressants
- Avoid: Contact with eyes
- Proper Use: Only with included applicators; never spray directly on skin
3 Steps to Using Cryo Professional Portable Cryosurgical System
Step 1 Saturate
Spray the applicator until droplets form.
Step 2 Acclimate
Allow the applicator to reach its effective temperature.
Step 3 Freeze
Apply the treatment to the lesion as directed.
Trusted by Medical Professionals
Mark H. CRNA, MSN, APN
Mark H. CRNA, MSN, APN
Mark H. CRNA, MSN, APN
Cryo Professional Portable Cryosurgical System Timeline
Learn more about the history of the Cryo Professional portable cryosurgical system, previously introduced to the market as Histofreezer®.
Frequently Asked Questions About Gebauer's Cryo Professional
What is cryosurgery?
Cryosurgery is a local treatment that uses extreme cold to destroy cells or tissue, allowing for the removal of warts or other skin lesions.
Is cryosurgery painful?
Patients may experience a mild burning sensation during cryosurgery, but the procedure does not typically require anesthesia.
What is the healing time for cryosurgery?
Healing time depends on the type of lesion, but in most cases, a blister will form after treatment and flatten within a few days. The lesion will then slough off within a few weeks.
Is Cryo Professional the same as Histofreezer®?
The Cryo Professional originated as Histofreezer®, invented in the late 1980s by a Dutch general practitioner and later acquired by Utermöhlen.
It was distributed by STC Technologies, which later became OraSure Technologies and acquired the rights to the patents, trademark and business from Utermöhlen. Utermöhlen continued manufacturing Histofreezer® for OraSure until 2015 and later manufactured the same product under the Cryo Professional brand name.
What are the reimbursement rates for the Cryo Professional surgery system?
Reimbursement rates for cryosurgery kits vary depending on the condition being treated and may range from $3,395.50 to $9,686.50, according to the latest Medicare data.