<img height="1" width="1" style="display:none" src="https://www.facebook.com/tr?id=1119689118113199&amp;ev=PageView&amp;noscript=1">
  • There are no suggestions because the search field is empty.
mobile-icon
Cryo
cryo-professional-icon

Treat Various Lesions With a Portable Cryosurgery System

Why send your patients to a specialist when you can treat common warts and skin lesions right in the office?

The Cryo Professional portable cryosurgery system for treatment of different types of benign skin lesions is convenient and cost-effective for physicians and healthcare professionals. Each kit includes cryogenic aerosol canisters, instructions for use, and single-use applicators, providing approximately 50 treatments.

prod-hero-pattren

Cryo Professional

Convenient For Patients. Cost‑Effective For You.

Each cryosurgery kit contains cryogenic aerosol canisters with dimethyl ether propane spray, single-use applicators, and instructions for use. The kit typically pays for itself within three to four applications. Cryo Professional is ready to use when you need it.

Cryo Professional Benefits

  • Easy to use and takes just minutes
  • Results similar to liquid nitrogen
  • Low cost per treatment
  • Profitable reimbursement
  • Ready to use

Cryo Professional Indications and Usage

The Cryo Professional cryosurgery system is cleared to treat a variety of warts and skin lesions, including: 

  • Verruca vulgaris (common wart)
  • Lentigo (age spots)
  • Verruca plana (flat wart)
  • Keratoses (sun spots)
  • Verruca plantaris (plantar wart)
  • Acrochordon (skin tags)
  • Condyloma (genital warts)
  • Molluscum contagiosum (water warts)

Part Numbers and Descriptions

  • UTM0400 Mixed Kit
    (2) 80mL canisters, (30) 2mm & (30) 5mm applicators
  • UTM0300 2mm Kit
    (2) 80mL canisters, (60) 2mm applicators
  • UTM0200 5mm Kit
    (2) 80mL canisters, (50) 5mm applicators

Download Cryo Professional Resources

guide

The Cryo Professional Guide

data sheet

Cryo Professional Safety Data Sheet

Cryo Professional instructions manual

Instructions for Use

Cryo Professional Application Videos

Video

Cryo Professional: Instructional Video

For the treatment of various benign skin lesions by professionals on patients.

Important Risk and Safety Information

Cryo Professional is flammable. Keep away from open flame and other potential ignition sources, including diathermy or other medical equipment. Use in a well-ventilated area. Consult a pediatrician for use on patients 4 and younger. Do not use if uncertain of diagnosis or if there is a possibility of cancer, or on patients with cryoglobulinemia, circulatory issues, or patients using immunosuppressant medication. Do not spray cryogen directly on skin or when applicator tip is in contact with skin. Avoid eye contact. Use only as a system with the supplied applicators. Freezing may alter skin pigmentation. Avoid freezing on peripheral arteries. Carefully read instructions prior to using this product.

CAUTION: Federal law restricts this device to sale by and on the order of a licensed healthcare practitioner.

cryo-1

More About Cryo Professional

Cryo Professional is designed to provide a convenient, effective approach to cryosurgical treatment in a variety of clinical settings. With its portable design and controlled application, it supports healthcare professionals in delivering precise, efficient care for a range of common skin lesions.

In the sections below, explore additional details about Cryo Professional, including how it works, its clinical applications, and key considerations for use.

Key Specs at a Glance

  • Onset Time: Seconds
  • Treatment Time: 15–40 seconds depending on lesion type
  • Contents: DMEP blend in an 80 mL aerosol can
  • Treatment Capacity: Approx. 50 applications per kit
  • Application Method: Spray-to-applicator
  • Indications: Warts, keratoses, molluscum contagiosum, lentigo, and more
two professionals discussing cryo professional

Designed for Patient Comfort and Practitioner Ease

Cryo Professional is quiet, fast, and its targeted spray method avoids direct cryogen-to-skin contact, which helps minimize discomfort.

With short treatment times and no tanks or tools, it’s a gentle, efficient option.

two cryo professional bottles

Cryo Professional vs. Liquid Nitrogen

Cryo Professional delivers cryosurgical performance comparable to liquid nitrogen, but without the drawbacks of bulk storage, or cryogen tanks.

Designed for simplicity and safety, it uses a non-toxic, non-pressurized dimethyl ether-propane (DMEP) blend and single-use applicators that make it easy for clinicians to apply consistent treatments without refrigeration, electricity, or protective gloves required.

It’s ready to use within seconds and stores easily in tight clinical spaces.

cryo professional kit

Clinical Track Record

Cryo Professional builds on over a century of innovation from Gebauer, the makers of Gebauer’s Ethyl Chloride®. Backed by evidence and practice, Cryo Professional has demonstrated safety and efficacy in both pediatric and adult dermatologic care. It’s trusted for treating a wide range of skin lesions and can deliver a profitable return after just a few uses.

Cryo professional kit with extra applicator tips

When to Choose Cryo Professional

Choose Cryo Professional when you need a safe, effective, and portable solution for treating benign skin lesions. It’s ideal for pediatric practices, urgent care, dermatology, and mobile health units and useful when time, space, and patient comfort are top priorities.

It’s also a smart alternative when liquid nitrogen systems are too costly, cumbersome, or impractical.

derm check

Cryo Professional Contents and Cost Per Treatment

Each Cryo Professional kit includes two 80 mL canisters and single-use applicators (quantities vary by kit type). Treatment costs are minimal. Kits typically pay for themselves in 3–4 uses, with up to 50+ treatments per kit.

Reimbursement rates vary by CPT code but can exceed $5,000 per kit depending on lesion type.

Cryo bottle

Evolution of Cryo Professional

Originally developed under the name Histofreezer®, the Cryo Professional system reflects Gebauer’s legacy of refining patient comfort tools. What started as a simpler alternative to liquid nitrogen has evolved into a precision-engineered solution with clinical-grade spray control, ergonomic handling, and a growing role in pediatric and outpatient dermatology care.

Cryo bottle with applicator tips

Storage, Shelf Life, Shipping

  • Storage: Store tightly sealed in a cool, ventilated space away from temperatures above 122°F (50°C)
  • Shelf Life: Up to 3 years from manufacturing date
  • Shipping: Classified as UN1950 AEROSOLS — flammable; special care required for transport
  • Disposal: Follow hazardous waste protocols. Do not puncture or incinerate
Cryo kit with more applicator tips

Safety Facts

  • Refrigerant: Non-toxic dimethyl ether-propane blend
  • Flammable: Yes – keep away from heat or electrical cautery equipment
  • Use only on: Patients age 4+ with benign lesions on intact skin
  • Do NOT use: On suspicious or pigmented lesions, or patients with circulatory issues, cryoglobulinemia, or immunosuppressants
  • Avoid: Contact with eyes
  • Proper Use: Only with included applicators; never spray directly on skin
nurses and doctors in a discussion

3 Steps to Using Cryo Professional Portable Cryosurgical System

Step 1 Saturate

Spray the applicator until droplets form.

steps-icon

Step 2 Acclimate

Allow the applicator to reach its effective temperature.

spray-icon

Step 3 Freeze

Apply the treatment to the lesion as directed.

Perform-icon
Read full instructions for use thoroughly before handling or using.

Trusted by Medical Professionals

My patients are especially thankful for dedication to excellence in order to put them at ease during an especially stressful time. As a Certified Registered Nurse Anesthetist, Pain Ease has allowed me to accomplish this successfully."

Mark H. CRNA, MSN, APN

My patients are especially thankful for dedication to excellence in order to put them at ease during an especially stressful time. As a Certified Registered Nurse Anesthetist, Pain Ease has allowed me to accomplish this successfully."

Mark H. CRNA, MSN, APN

My patients are especially thankful for dedication to excellence in order to put them at ease during an especially stressful time. As a Certified Registered Nurse Anesthetist, Pain Ease has allowed me to accomplish this successfully."

Mark H. CRNA, MSN, APN

testi-pattern

Cryo Professional Portable Cryosurgical System Timeline

Both Utermöhlen and Gebauer Company are family-owned medical device companies with more than 120 years of expertise in product development and distribution.

Learn more about the history of the Cryo Professional portable cryosurgical system, previously introduced to the market as Histofreezer®.

Frequently Asked Questions About Gebauer's Cryo Professional

What is cryosurgery?

Cryosurgery is a local treatment that uses extreme cold to destroy cells or tissue, allowing for the removal of warts or other skin lesions.

Is cryosurgery painful?

Patients may experience a mild burning sensation during cryosurgery, but the procedure does not typically require anesthesia.

What is the healing time for cryosurgery?

Healing time depends on the type of lesion, but in most cases, a blister will form after treatment and flatten within a few days. The lesion will then slough off within a few weeks.

Is Cryo Professional the same as Histofreezer®?

The Cryo Professional originated as Histofreezer®, invented in the late 1980s by a Dutch general practitioner and later acquired by Utermöhlen.

It was distributed by STC Technologies, which later became OraSure Technologies and acquired the rights to the patents, trademark and business from Utermöhlen. Utermöhlen continued manufacturing Histofreezer® for OraSure until 2015 and later manufactured the same product under the Cryo Professional brand name.

What are the reimbursement rates for the Cryo Professional surgery system?

Reimbursement rates for cryosurgery kits vary depending on the condition being treated and may range from $3,395.50 to $9,686.50, according to the latest Medicare data. 

Contact Gebauer About Cryo Professional