Utermöhlen Cryo Professional Portable Cryosurgical System Timeline

Founded in 1880, Royal Utermöhlen is a long-standing Dutch manufacturer of wound care and related products. They are the original marketer and manufacturer of the dimethyl ether cryosurgical product archetype invented by Dutch general practitioner Dr. Willem Swart, which they introduced in Europe in the late 1980’s, and the US in 1991. These products are commonly referred to today as cryosurgical “H” type products.

Like Utermöhlen, Gebauer Company is a 120-year-old family-owned medical device company. The two companies have similar high standards and objectives and have identified a variety of business synergies resulting in this distribution arrangement.

Other than the brand name under which it is sold, Cyro Professional is the same trusted Dimethyl Ether (DME)-based formula and applicator used by US practitioners since 1991.

Cryo Professional and other “H” type products reach a sub-lethal freeze temperature of -55°C delivered by applicators and are FDA cleared for treatment of nine indications. Cryosurgical “V” type products typically utilize cone applicators and reach a freeze temperature of -70°C, enabling them to treat several additional less common indications.

Unlike liquid nitrogen, which requires frequent refilling of dispensers and bulk storage of cryogen, Cryo Professional is provided in a convenient aerosol format which requires no additional equipment. It is ready to use whenever the need arises, making it an ideal choice for general practitioners such as family and pediatric practices, podiatry, and others for treatment of warts and other common lesions.

Cryo Professional has a shelf life of 3 years from date of manufacture. See canister and kit labeling for expiry.

Yes, Cryo Professional contains dimethyl ether, propane, butane, isobutane and, like isopropyl alcohol and other common substances used in clinics and similar facilities, is flammable.

Cryo Professional should be stored at normal room temperature up to 77°F and may be kept ready to use on a countertop. See Instructions for Use and product SDS for additional information. The product should be stored in a cool and dry place at a maximum of 25°C. It should not be stored in direct sunlight.

If Cryo Professional is purchased from a major distributor and delivered by the distributor’s fleet truck, there will be no hazardous shipping fee. However, if your shipment is made via an alternative carrier such as UPS, USPS, or FedEx, HAZMAT shipping fees may apply. Keep in mind that such fees are applied per shipment, no matter how many units are purchased, and savings may result by purchasing in larger quantities.

Each Cryo Professional kit includes two canisters of liquid cryogen. Depending on the applicator used, this should be sufficient to administer approximately fifty treatments. Keep in mind that the smaller 2mm applicator will require slightly less cryogen than the larger 5mm applicator, and that there will be some variation between individual clinicians.

Contact your Gebauer sales representative to discuss samples or to arrange for a demonstration. Please note that sample quantities are limited. Keep in mind that since Cryo Professional is used for a variety of reimbursable procedures, a kit typically pays for itself within 3-4 uses.

No, Cryo Professional is supplied only in kit form with an appropriate supply of applicators in each.

Cryo Professional is FDA cleared for the treatment of Verruca vulgaris (common wart), Verruca plana (flat wart), Verruca plantaris (plantar wart), Condyloma (genital warts), Lentigo (age spots), Keratoses (sun spots), Achrochordon (skin tags), Molluscum Contagiosum (water warts). See Instructions for Use to review specific indications and treatment guidelines.

No, the Cryo Professional system is for use only on indicated benign lesions. Refer to the Instructions for Use for more information.

Please read the Instructions for Use booklet thoroughly before handling or using the Cryo Professional product.

Applicators are designed to be single-use disposable and not to be used on more than one patient. An applicator may be used on more than one treatment site of a single patient but should not be used on different types of lesions on the same patient or be re-saturated. If the applicator is no longer sufficiently cold, a new applicator should be used.

A 2mm applicator will remain saturated and cold for approximately 90 seconds, while a 5mm applicator will last around 120 seconds. Additional treatments may be administered within these cycles. It is not recommended that applicators be saturated again and refrozen for a second use. If the applicator is no longer sufficiently cold, a new applicator should be used for additional treatments.

The safety of Cryo Professional applied to pregnant or breastfeeding patients has not been determined.