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PainEase One™

Topical Anesthetics Reimagined for Modern Healthcare

The Same Relief In a Single Package

In today's healthcare environment, every step matters. PainEase One provides a convenient single-use topical anesthetic solution designed to help clinicians deliver care efficiently while supporting consistent application practices across procedural settings.

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PainEase OneTM

Single-Use Topical Anesthetic.

Designed for Modern Clinical Practice

Healthcare organizations face growing pressure to improve efficiency, standardize processes, and optimize resources while maintaining high-quality patient care.

PainEase One™ is a ready-to-use, single-use topical anesthetic designed to help clinicians and healthcare leaders meet these challenges. For more than a century, healthcare providers have trusted Gebauer Company for innovative solutions that enhance patient comfort.

PainEase One Indications and Usage

Gebauer’s PainEase One is intended for topical application on intact skin, minor open wounds, and intact oral mucous membranes to temporarily control pain associated with:

  • Immunizations
  • IV starts
  • Joint injections
  • Blood draws
  • Incision and drainage of small abscesses
  • Foreign body removal
  • Lancing boils
  • Skin tag removal
  • Suturing and suture removal
  • Cosmetic procedures

PainEase One Product Details

  • PainEase One Stream
    0.4 fl. oz can, P/N 0386-0008-05

Patient Comfort That Keeps Up With You

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What it is

A single-use, ready-to-use topical anesthetic by Gebauer.

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Who uses it

Physicians, nurse leaders, and in physician offices, hospitals, ambulatory care, and specialty clinics.

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Procedures supported

Pre-procedural topical anesthesia for outpatient, hospital, or office-based settings.

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Workflow fit

Replaces multi-use containers, standardizes dosing, simplifies training, and streamlines inventory and protocol consistency.

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Support Consistency Across Care Teams

Nurse leaders play a critical role in driving quality outcomes and operational efficiency.

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With PainEase One, nursing teams can benefit from:

A Convenient Application

Provide a simple, ready-to-use option whenever and wherever needed

Simplified Training

Streamline routine operations, making the clinicians' experience more straightforward

Standardized Care

Give teams a unified approach to easing patients' pain before procedures

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Benefits for Healthcare Organizations

More Efficient Workflows

Clinicians can provide faster care with ready-to-use, disposal solutions.

Eliminates Re-Use


There's no need to store partly used cans; just use them once and throw them away.

Supports A Better Patient Experience


Research shows using topical anesthetics prior to minor procedures eases patient anxiety and pain.

Supporting Clinical and Operational Goals

Healthcare leaders are seeking solutions that contribute to both quality care and operational performance.

PainEase One was developed to help organizations:

  • Improve procedural efficiency
  • Support staff productivity
  • Enhance care standardization
  • Simplify product management
  • Reduce workflow complexity
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3 Steps on How to Use Pain Ease

Step 1 Prep

  • Have all necessary equipment ready
  • Prepare the skin per your protocol
  • Prepare the patient for the cold effect
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Step 2 Spray

  • Hold the can 3 to 7 inches from treatment site, about a can’s length away
  • Spray steadily 4 to 10 seconds or until the skin begins turning white, whichever comes first
  • Do not spray longer than 10 seconds
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Step 3 Perform

  • Perform the procedure
  • The anesthetic effect lasts about one minute
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Refer to application instructions for full details
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Find the best topical anesthetic option for your organization:

Product
LIDOCAINE-
PRILOCAINE (EMLA)
L.M.X. 4®
J-Tip® Needle-Free Injection System
Lidocaine Injection
Description

Topical anesthetic skin refrigerant

Nondrug, nonflammable formula

1,1,1,3,3-Pentafluoropropane & 1,1,1,2-Tetrafluoroethane

Topical anesthetic cream

Lidocaine 2.5%, Prilocaine 2.5%

Topical anesthetic cream

Lidocaine 4%

Pre-sterilized, single use, disposable device which disperses medication in spray-like pattern into the subcutaneous tissue

Xylocaine (Lidocaine)

Sterile solution of lidocaine hydrochloride in water

1% or 2% Lidocaine HCl (10mg/mL or 20mg/mL)

FDA-Approved Indications

Temporarily controls the pain associated with needle procedures, injections, IV starts, venipuncture, and minor surgical procedures

Can be applied to intact skin, intact oral mucous membranes, and minor open wounds

Normal intact skin for local analgesia. Genital mucous membranes for superficial, minor surgery & as pretreatment for infiltration anesthesia
Minor cuts, minor burns, minor skin irritations, abrasions, sunburn, insect bites
Intended use for the subcutaneous administration of Xylocaine
Production of local or regional anesthesia by infiltration techniques
Method of Application
Spray 4-10 seconds and immediately perform procedure
Apply cream under an occlusive dressing

Apply cream

Occlusive dressing recommended for pediatric use

Device must be filled with lidocaine

Once filled, position at a 90-degree angle to the skin and press firmly, approximately 1/8 inch into the skin

Requires syringe

Dosage variance and different concentrations

Important Risk and Safety Information:

Consult your pediatrician when using on children 4 years old and younger. Do not use on large areas of damaged skin, puncture wounds, animal bites or serious wounds. Do not spray in eyes. Over spraying may cause frostbite. Freezing may alter skin pigmentation.

Use caution when using product on persons with poor circulation. Apply only to intact oral mucous membranes. Do not use on genital mucous membranes. The thawing process may be painful and freezing may lower resistance to infection and delay healing. If skin irritation develops, discontinue use. 

CAUTION: Federal law restricts this device to sale by or on the order of a licensed healthcare practitioner.

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Frequently Asked Questions About Gebauer's PainEase One

What Is PainEase One used for?

Like the standard PainEase, PainEase One is a topical anesthetic skin refrigerant used to instantly and temporarily control the pain associated with needle procedures, minor surgical procedures, and minor sports injuries. Clinicians use it before venipuncture, IV starts, injections, and immunizations. It's the same trusted formulation, in a convenient single-use format.

How does PainEase One work?

PainEase One creates cooling sensation when it evaporates on the skin instantly, drawing heat away from the surface. This provides relief from the pain of minor procedures. It begins working in just 4–10 seconds and is a non-flammable, non-drug solution that any licensed healthcare practitioner can use without a doctor's order.

How is PainEase One different from standard PainEase?

The formulation, indications, and how it works are the same. The only difference is the format. PainEase One comes in a single-use package designed to be used with one patient and then discarded, which supports a simpler, more standardized bedside workflow and eliminates the need to track and re-cap a shared can between patients.
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A Smarter Approach to Topical Anesthetics

Discover how PainEase One can help support your organization's clinical, operational, and patient care objectives.

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Download PainEase One Resource